A front row injury crisis during last month's autumn internationals led to a surprise international recall for the World Cup winner, with suggestions then circulating that Botha is keen to reignite his Springbok career with a move back to southern hemisphere rugby.
But Ulster's director of Rugby Operations has made it clear that there is 'no way' the 29-year-old will be walking out of his contract.
"No way (is he on his way home]," Humphreys told the Irish Independent.
"Brian McLaughlin and the coaching staff see BJ as one of the cornerstones of what is a young Ulster team and he is very much a part of what we are trying to achieve in terms of bringing the team through.
"He is enjoying his time at Ulster Rugby and plays a hugely important role for us."
Botha will miss Friday night's Magners League clash against Glasgow Warriors at Ravenhill with a knee injury but should return in time for the Boxing Day clash at Leinster.
