Anscombe has also made three positional changes, the most notable of which sees captain John Afoa switch from tight-head to loose-head prop. It will be the first time that Afoa has started for Ulster at loose-head.
Andrew Trimble moves from outside centre to his more familiar position on the right wing, while Michael Allen switches flanks and will start at number 11.
Nigel Brady, Callum Black, Neil McComb and Ali Birch drop to the bench alongside Ricky Lutton, Paul Marshall, Niall O'Connor and Chris Cochrane.
Commenting on the selection, Mark Anscombe said: "It is good to give the guys who are on the periphery of the international team some game time. We welcome them back and with the experience that they bring, they will only strengthen our side."
Ulster XV and replacements to face Benetton Treviso, RaboDirect PRO12, Ravenhill, Friday 1st March 2013 (kick off 19:05):
(15-9): R Andrew, A Trimble, D Cave, S Olding, M Allen, P Jackson, R Pienaar;
(1-8): J Afoa, R Herring, D Fitzpatrick, L Stevenson, D Tuohy, I Henderson, M McComish, R Diack;
Replacements (16-23) N Brady, C Black, R Lutton, N McComb, A Birch, P Marshall, N O'Connor, C Cochrane.
There are fewer than 300 tickets remaining for the match. For tickets, or for further information on Ulster Rugby games, go to ulsterrugby.com